Cabozantinib with nivolumab is the first-line treatment for kidney cancer, called as renal cell carcinoma (RCC).

Cabozantinib is a tyrosine kinase inhibitor. It works by blocking the action of an abnormal protein that signals cancer cells to multiply. It helps slow or stop the spread of cancer cells. Nivolumab is a programmed death receptor-1 (PD-1) blocking antibody. It is a type of immunotherapy.

How should I take the combination of cabozantinib and nivolumab?

Nivolumab comes as a solution injected into vein by your doctor in a medical facility. It is given in combination with cabozantinib 40 mg orally once daily without food.

Do not stop taking the treatment combination without talking to your doctor. You can help them by tracking your side effects in Ankr.

What are the side effects of this combined drug intake?

• Diarrhea (loose stools)
• Fatigue (Tiredness)
• Hepatotoxicity
• Hand-Foot Syndrome
• Stomatitis
• Rash
• Hypertension
• Hypothyroidism
• Musculoskeletal pain
• Appetite loss (Anorexia)
• Nausea
• Abnormal taste (Dysgeusia)
• Abdominal Pain (Bellyache)
• Cough
• Upper respiratory tract infection