Table of Contents
What is malignant pleural effusion?

A malignant pleural effusion (MPE) is the build-up of fluid and cancer cells that collects between the chest wall and the lung.
Pleura surrounding your lungs and lining the inside of your chest. A small amount of fluid in this area is normal. It helps the lungs move in your chest as you breathe. Cancer and other conditions can cause fluid to build up. A pleural effusion can be serious and life-threatening, but it is treatable.
How bad is my malignant pleural effusion?
Mild: Asymptomatic; clinical or diagnostic observations only; intervention not indicated
Moderate: Symptomatic; medical intervention indicated (fat-restricted diet); thoracentesis or tube drainage indicated
Severe: Severe symptoms; elective operative intervention indicated
How to manage mild symptoms?
Treatment for a pleural effusion can be given in a hospital or an outpatient setting. There are several methods (thoracentesis, tube thoracostomy, Catheter, shunt, surgery) available to remove the fluid.
How to manage severe malignant pleural effusion? ?
It can cause uncomfortable side effects. Seek medical help if you experience
- Shortness of breath
- Dry cough
- Pain
- Feeling of chest heaviness or tightness
- Inability to lie flat
- Inability to exercise
What are the causes?
- Certain types of cancer:
- Breast Cancer
- Lung Cancer
- Lymphoma
- Mesothelioma
- Ovarian Cancer
2. Cancer treatments: Radiation therapy, chemotherapy, abdominal surgery, and certain medications can cause pleural effusion.
3. Other health conditions:
- Blood clot in the lungs (pulmonary embolism)
- Heart disease or heart failure
- Kidney disease
- Liver disease
- Pneumonia
- Airway obstruction or lung collapse
- Poor nutrition, causing low protein levels